
The NOX-D20 aptamer complex. (A) Cartoon representation of the structure of the NOX-D20 aptamer bound to C5a (PDB:4WB2; Yatime et al. 2015). The C5a four-helix bundle is highlighted by a translucent molecular surface. The antiparallel duplex and G4 structural elements of NOX-D20 are represented in white and salmon, respectively. Green spheres denote Ca2+. (B) Schematic of the NOX-D20 quadruplex.










