A mark of disease: how mRNA modifications shape genetic and acquired pathologies

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FIGURE 4.
FIGURE 4.

Pseudouridine (Ψ) modification. The first column displays the Ψ structure, consensus motifs and lists the main writers of Ψ in mRNAs. The motif was obtained by data in Carlile et al. (2019) and plotted with WebLogo (Crooks et al. 2004). The central column highlights Ψ distribution (Carlile et al. 2019) and functions in mRNA fate. The third column displays the disorders associated with dysregulated pseudouridylation.

This Article

  1. Published in Advance December 29, 2020, doi: 10.1261/rna.077271.120 RNA 27: 367-389

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