A mark of disease: how mRNA modifications shape genetic and acquired pathologies

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FIGURE 3.
FIGURE 3.

N6-methyladenosine (m6A) modification. The first column displays the m6A structure, consensus motif and m6A machinery factors. The motif was obtained by data in Linder et al. (2015) and plotted with WebLogo (Crooks et al. 2004). The central column highlights the m6A distribution and functions in mRNA fate, while the third column displays m6A-associated disorders and the organs to which they are associated.

This Article

  1. Published in Advance December 29, 2020, doi: 10.1261/rna.077271.120 RNA 27: 367-389

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