C-to-U editing. The first column displays the structures of cytidine and uridine involved in the deamination, the consensus motif and the C-to-U editing main effectors. The motif was obtained by data in Rosenberg et al. (2011) and plotted with WebLogo (Crooks et al. 2004). The central column shows the percentage of editing in the mRNA regions and the functions in mRNA fate. The third column displays C-to-U editing-associated disorders and the organs to which they are associated. Considering that little is known on the significance of RNA editing by APOBEC3A and APOBEC3G, all features in the figure relate to APOBEC1, and APOBEC3A/APOBEC3G are only mentioned in parentheses.
