Insertions of codons encoding basic amino acids in H7 hemagglutinins of influenza A viruses occur by recombination with RNA at hotspots near snoRNA binding sites

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FIGURE 4.
FIGURE 4.

Putative snoRNA binding at the recombination sites of HA RNAs with other influenza A virus segments. The sequences of NP and M segments involved in the recombination are from the LPAI progenitors: (A) Orlich et al. (1994); (B) Suarez et al. (2004); (C) Hirst et al. (2004). Chicken orphan H/ACA snoRNA GGoACA5 has been identified by Shao et al. (2009). Notations are similar to those in Figure 2.

This Article

  1. Published in Advance November 13, 2020, doi: 10.1261/rna.077495.120 RNA 27: 123-132

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