Human spliceosomal snRNA sequence variants generate variant spliceosomes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 6.
FIGURE 6.

snRNA variants are expressed and incorporated into splicing complexes. Histogram of the proportion of canonical (gray) versus variant (colored) snRNAs from total RNA, Sm IPs, snRNPs, and spliceosomes isolated from 293T cells. For U5 snRNA, the five major variants are labeled, and the unlabeled box corresponds to the sum of the three minor variants. The x-axis is log10 scaled.

This Article

  1. Published in Advance July 7, 2021, doi: 10.1261/rna.078768.121 RNA 27: 1186-1203

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA