Sulfonated inhibitors of the RNA editing ligases validate the essential role of the MRP1/2 proteins in kinetoplastid RNA editing

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FIGURE 2.
FIGURE 2.

C35 affects the RNA binding activity of recombinant MRP1/2 proteins. Increasing concentrations of the respective proteins were incubated with 32P-labeled gA6[14] gRNA in the absence and presence of C35 at 10 µM: (A) rMRP1/2 proteins and (B) rKREPA4. The positions of free gA6[14] and protein-bound gA6[14] as resolved on the native TBE gels are indicated.

This Article

  1. Published in Advance April 10, 2020, doi: 10.1261/rna.075598.120 RNA 26: 827-835

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