
Schematic of the different levels of compaction of mRNAs. (i) Nuclear and nontranslating mRNAs represent the most compact form. (ii) Ribosomes decompact the mRNA by unfolding the mRNA. (iii) mRNAs that are more engaged in translation (more ribosomes loaded) are more decompact than mRNAs that are not as well translated. (iv) Finally, the theoretical fully expanded mRNA.










