Solution structure and RNA-binding of a minimal ProQ-homolog from Legionella pneumophila (Lpp1663)

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FIGURE 6.
FIGURE 6.

Variation of the length of oligo U does alter the binding affinity of Lpp1663. ITC thermograms of Lpp1663 titrated with oligo U8 and oligo U4. Compared to oligo U6 (29 µM) oligo U4 binds to Lpp1663 with a very similar affinity while oligo U8 binds with an approximately fourfold increased affinity.

This Article

  1. Published in Advance September 28, 2020, doi: 10.1261/rna.077354.120 RNA 26: 2031-2043

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