Processing of Alu small RNAs by DICER/ADAR1 complexes and their RNAi targets

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FIGURE 6.
FIGURE 6.

Alu siRNAs target CDCP1 in an AGO2-dependent manner. (A) Western blotting analysis of CDCP1 (full-length 135 kDa bands) in Alu siRNA-transfected HeLa cells at 72 h post-transfection. β-actin was used as a loading control. (B) The CDCP1 levels in Alu siRNA-transfected AGO2 knockdown cells were evaluated by western blotting. HeLa cells were treated with AGO2 siRNA twice. Alu siRNA and the second AGO2 siRNA were transfected into HeLa cells 48 h after the first AGO2 siRNA treatment.

This Article

  1. RNA 26: 1801-1814