Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus

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FIGURE 7.
FIGURE 7.

Nonsynonymous and synonymous site sequence divergence of polyprotein sequences of different HCV genotypes. Sequence distances between each study polyprotein sequence of gts 1a, 1b, and 3a from a reconstructed consensus (ancestral) sequence of each genotype at (A) nonsynonymous, and (B) synonymous sites. Red bars show mean values; differences in the distribution of MFED values were calculated using the Kruskall–Wallace test; significant values shown in red bold type.

This Article

  1. RNA 26: 1541-1556