
Nonsynonymous and synonymous site sequence divergence of polyprotein sequences of different HCV genotypes. Sequence distances between each study polyprotein sequence of gts 1a, 1b, and 3a from a reconstructed consensus (ancestral) sequence of each genotype at (A) nonsynonymous, and (B) synonymous sites. Red bars show mean values; differences in the distribution of MFED values were calculated using the Kruskall–Wallace test; significant values shown in red bold type.










