Inhibition of SF3B1 by molecules targeting the spliceosome results in massive aberrant exon skipping

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FIGURE 3.
FIGURE 3.

Analysis of different splicing events following sudemycin D1 treatment. (A) Schematic illustration of different splicing events. (B) Exon skipping events predominate in Rh18 cells following sudemycin D1 treatment. (C) Preferred exons are significantly longer than skipped exons after sudemycin D1 treatment. (D) Summary of different splicing events in the time course experiments for Rh18 cells.

This Article

  1. Published in Advance May 29, 2018, doi: 10.1261/rna.065383.117 RNA 24: 1056-1066

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