
Division into active and inactive pools creates a selection opportunity. (A) Pool populations consist of active and persistent inactive pools. Fractions of 1000 sporadically fed cross-templating pools receiving 5 mM nucleotides that have made product (green circles; active) and not made product yet (blue circles; inactive) are plotted versus pool age in days. (B) Fraction templated synthesis (ftemp) in 1000 active, average, and inactive pools from A, plotted versus pool age in days.










