Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor

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FIGURE 3.
FIGURE 3.

Effect of ptRNase-treatment on tRF levels in wild-type and ΔRNH1 HeLa cells. (A) Principal component analysis of normalized tRF levels in ANG-, RNase 1-, or untreated cells. (B) Abundance of tRFs in ANG-treated ΔRNH1 cells. Values are the average of three biological replicates. (C) Abundance of tRFs in ANG-treated wild-type cells. (D) Predicted G-quadruplex forming motifs in up-regulated tRFs.

This Article

  1. Published in Advance May 10, 2018, doi: 10.1261/rna.065516.117 RNA 24: 1018-1027

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