Piwi, dicer-2 double mutant in heads does not drastically affect previously reported piwi-regulated genes in gonads. Boxplots of fold change for genes with reference genome TE insertions in their genomic boundaries do not suggest a trend for these genes to become derepressed across any of the tested mutant conditions (x-axis). We compared genes without TE insertions (red boxes) with genes with insertion of TE of any family (blue boxes, Aa), or with TE insertions that are up-regulated in dicer2 homozygous (blue boxes, Ab), piwi homozygous (Ac), or piwi, dicer-2 double homozygous mutants (Ad). (B) Boxplots of the distribution of fold changes for genes with DNA Damage Gene Ontology terms and (C) genes that have been reported to host piRNA production from their UTRs.
