Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis

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FIGURE 3.
FIGURE 3.

Flowchart and establishment of three zebrafish slbp2 mutant lines. (A) Flowchart and phenotypes of three zebrafish slbp2 mutant lines. (B) The relative expression of slbp2 in MZslbp2Δ4−/− and wild-type embryos at the 256-cell and high stages detected by qPCR. Zslbp2Δ4−/−: zygotic slbp2 F2 homozygous mutant; Mslbp2Δ4+/−: maternal slbp2 F3 heterozygous mutant; MZslbp2Δ4−/−: maternal-zygotic slbp2 F3 homozygous mutant.

This Article

  1. Published in Advance September 5, 2018, doi: 10.1261/rna.067090.118 RNA 24: 1738-1748

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