dsRNAs cluster on the distal arms of two Caenorhabditis species. (A) The distribution of EERs (black) and random expressed regions (gray) over the six major C. elegans chromosomes divided into 10 equal segments. The center of each chromosome is defined as position 0, the end of the left arm is −0.5 and the end of the right arm is position 0.5. (B) Smoothed distributions of average intron ΔG/nt across C. elegans (blue) and Caenorhabditis briggsae (red) chromosomes. More structured introns have lower (more negative) ΔG/nt values. Vertical dotted lines depict chromosome arm and center domains, determined by intron ΔG/nt (Materials and Methods). (Adapted from Reich and Bass 2019, with permission from Cold Spring Harbor Laboratory Press.) (C) The distribution of inverted repeats (IRs; black) and tandem repeats (TRs; gray) across relative chromosomal segments. (D) The percentages of the entire C. elegans genome, IR regions, and TR regions that overlap annotated gene features.
