Combinatorial interplay of RNA-binding proteins tunes levels of mitochondrial mRNA in trypanosomes

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FIGURE 2.
FIGURE 2.

MRP1 iCLIP results. (A) Percentage of total MRP1 iCLIP tags obtained from each of the three mRNA categories. (B) Transcript length-normalized percentage of total MRB1 iCLIP tags obtained from each of the three mRNA categories. (C) Fold enrichment of MRB8170, MRB4160, and MRP1 iCLIP tags relative to mapped mRNA-seq read counts for three mRNA categories. (D) Genomic browser snapshots of MRP1 and MRB8170 presence on the pre-edited forms of ND8 (pan-edited) and CYB (minimally edited), and never-edited ND4 mRNAs. White lines show the approximate distribution of editing sites on ND8 and CYB. See also Supplemental Figures S1–S5.

This Article

  1. Published in Advance August 17, 2018, doi: 10.1261/rna.066233.118 RNA 24: 1594-1606

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