Dynamic temperature-sensitive A-to-I RNA editing in the brain of a heterothermic mammal during hibernation

Editing sites are predominantly located in SINE elements in intronic sequences. (A) Genomic distribution of cold-enriched editing sites. Annotations were derived using both the Ensembl 85 annotation and the novel transcriptome built in this study. (B) Distribution of constitutively edited sites. (C) Number of cold-enriched editing sites within repeat classes and repeat families defined by repeatMasker annotations. (D) Repeat classification for constitutively edited sites.