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Crystal structure of a guanidine-I riboswitch from S. acidophilus (Protein Data Bank code: 5t83; Reiss CW, Xiong Y, Strobel SA. 2017. Structural basis for ligand binding to the guanidine-I riboswitch. Structure 25: 195–202). Image details show RNA—ribbon representation, gray; guanidine—spacefilling represention, red; metal ions not shown. The image was generated with the Jena3D Viewer (jena3d.leibniz-fli.de). Cover image provided by the Jena Library of Biological Macromolecules—JenaLib (jenalib.leibniz-fli.de).