Assessment and comparison of thermal stability of phosphorothioate-DNA, DNA, RNA, 2′-F RNA, and LNA in the context of Phi29 pRNA 3WJ

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FIGURE 2.
FIGURE 2.

Melting of homogeneous 3WJs on TGGE. (A) Melting of 3WJPS-DNA from 10°C to 38°C. (B) Melting of 3WJDNA from 20°C to 60°C. (C) Melting of 3WJRNA from 40°C to 80°C. (D) Melting of 3WJ2′-F from 40°C to 80°C. (E) Melting of 3WJLNA from 30°C to 80°C. Black arrow and number indicate Tm.

This Article

  1. Published in Advance October 19, 2017, doi: 10.1261/rna.063057.117 RNA 24: 67-76

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