FIGURE 3.
Improved peak picking using a peak-sharpening protocol. (A) The peak-sharpening algorithm computes an enhanced data trace (dashed gray line) that has significantly exaggerated the peaks and troughs compared to the raw data trace (solid black line). (B) The enhanced data allow for more robust peak assignment. In the example shown, five out of 10 peaks can be assigned using the raw data (blue triangles), whereas all 10 peaks are properly assigned when using the peak-sharpened, enhanced data (red circles).
