Conservation of tRNA mimicry in the 5′-untranslated region of distinct HIV-1 subtypes

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FIGURE 1.
FIGURE 1.

Secondary structure of MAL 123–349 predicted by mfold. The PBS/TLE (left) and Psi (ψ) (right) domains are shown in the dotted boxes. The A-rich stem–loop is shown in green, the PBS in red, and the 23-nt subtype A-specific insertion in blue. The C277G DIS mutant construct is indicated by the circled C. To facilitate in vitro transcription, two 5′ G's, not encoded by HIV-1, were added to this construct (gray).

This Article

  1. Published in Advance August 31, 2017, doi: 10.1261/rna.062182.117 RNA 23: 1850-1859

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