Regulatory network formed by trans-acting sRNAs and cognate mRNAs in A. pleuropneumoniae. The novel sRNAs described in this work have the potential to bind several mRNA targets, many of which are shared by more than one sRNA, possibly configuring an entangled network of gene regulation in A. pleuropneumoniae. The sRNA candidates’ names are depicted in white rectangles (Arrcs) and their mRNA connections are illustrated by thick black lines. The other putatively exclusive gene targets are linked to their respective regulatory RNA by gray lines. Targets that may be involved with either virulence or stress resistance are highlighted in black and gray, respectively.
