A computational strategy for the search of regulatory small RNAs in Actinobacillus pleuropneumoniae

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FIGURE 2.
FIGURE 2.

Computational prediction of small regulatory RNAs in A. pleuropneumoniae. (A) The sRNA candidates were defined as those predicted by at least two out of four (BLAST/Rfam, SIPHT, Infernal, and RNAz) algorithms with different approaches. As shown by the Venn diagram's intersections, the number of final candidates selected adopting this criterion was 23. (B) A CRISPR locus was also searched by using the software CRISPRFinder. For the A. pleuropneumoniae reference strain L20, a total of 26 direct repeats, separated by 25 spacers (gray) and surrounded by CRISPR-associated genes (arrows), were found.

This Article

  1. Published in Advance July 11, 2016, doi: 10.1261/rna.055129.115 RNA 22: 1373-1385

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