ATPγS stalls splicing after B complex formation but prior to spliceosome activation

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FIGURE 4.
FIGURE 4.

Electron microscopy of affinity-purified BATPγS complexes. (A) Overview of negatively stained BATPγS complexes. (B) Gallery of class averages of BATPγS complexes. (C) Typical class averages of B complexes purified after 6 min of splicing in the presence of ATP (Wolf et al. 2009). (D) Schematic representation of the human B complex, with main structural features labeled.

This Article

  1. Published in Advance July 13, 2016, doi: 10.1261/rna.057810.116 RNA 22: 1329-1337

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