Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs

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FIGURE 2.
FIGURE 2.

Target mRNAs of Rrp6 protein. (A) Frequency distribution of WT/rrp6Δ FPKM ratios of mRNA targets of Rrp6, defined as accumulating significantly by Cuffdiff (P < 0.01). The bin width is 0.05. (B) Frequency distribution of rrp6-cat/rrp6Δ FPKM ratios of mRNA targets of Rrp6, defined as accumulating significantly by Cuffdiff (P < 0.01). (C) Histogram showing the distribution of rrp6-cat/rrp6Δ FPKM ratios of Mmi1 target mRNAs (blue) and all mRNA targets of Rrp6 (green). (D) Frequency histogram showing the distribution of rrp6-cat/rrp6Δ FPKM ratios of iron homeostasis mRNAs (brown) and all mRNA targets of Rrp6 (green).

This Article

  1. Published in Advance July 11, 2016, doi: 10.1261/rna.051490.115 RNA 22: 1311-1319

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