Nucleotide specificity of the human terminal nucleotidyltransferase Gld2 (TUT2)

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FIGURE 5.
FIGURE 5.

Phylogeny of the TUTase/PAP superfamily. Gld2 is most closely related to the genuine uridylyltransferases TUT4/TUT7. Known enzymatic activities are color-coded. (Purple) UTP preference; (green) ATP preference; (black) unknown. Bootstrap values over 90% are denoted with a star. Sequence data were downloaded from the Integrated Microbial Genomes database. The tree was calculated with PHYML using a BioNJ starting tree and SPR tree search followed by NNI branch swapping to optimize the tree. Bootstrap values were computed according to the Shimodaira–Hasegawa reestimation of log-likelihood test implemented in PHYML.

This Article

  1. RNA 22: 1239-1249