A systematic computational analysis of the rRNA–3′ UTR sequence complementarity suggests a regulatory mechanism influencing post-termination events in metazoan translation

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FIGURE 3.
FIGURE 3.

Distribution of regions with statistically significant complementarity to 3′ UTRs on available secondary structures of metazoan 18S rRNAs. Secondary structures of 18S rRNAs of D. melanogaster (A), X. laevis (B), R. norvegicus (C), and H. sapiens (D) are shown. All initially identified, statistically significant regions of complementarity between the first 50 nt of 3′ UTRs and 18S rRNAs of these four species were projected onto their 2D structures and visualized in green. The regions that exhibit evolutionary conservation are highlighted in red and designated as ECRCs i–iv.

This Article

  1. RNA 22: 957-967