FIGURE 4.
ERK-selective inhibitor decreases mistranslation in GAA (Glu) and GAG (Glu) stable lines during oxidative stress. Cells stably transfected with mCherry mutants were incubated with or without the FR180204 inhibitor and Arsenite for 12 h, followed by flow cytometry to determine the proportion of cells with mCherry fluorescence. (A) Histogram shows the distribution of mCherry fluorescence intensity for GAA (Glu) cells. (B) Histogram shows the distribution of mCherry fluorescence intensity for GAG (Glu) cells. In all cases, the histograms represent the average of at least three experimental replicates from two separate experiments.
