Fingerprinting the junctions of RNA structure by an open-paddlewheel diruthenium compound

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FIGURE 3.
FIGURE 3.

(A) FMDV IRES secondary structure showing OPW-Ru (left) and NMIA plus DMS (right) reactive positions. The location of IRES domains (2–5) is indicated. Nucleotide numbers are used as in Lozano and Martinez-Salas (2015). (B) RNA reactivity of the apical region of domain 3 (nts 120–262) toward NMIA (light blue), IA (dark blue), 1M7 (light green), 1M6 (dark green), and OPW-Ru (red). OPW-Ru reactive positions are depicted on A (left panel) and B.

This Article

  1. Published in Advance January 12, 2016, doi: 10.1261/rna.054353.115 RNA 22: 330-338

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