Fingerprinting the junctions of RNA structure by an open-paddlewheel diruthenium compound

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FIGURE 2.
FIGURE 2.

FMDV IRES reactivity toward OPW-Ru analyzed by primer extension. (A) Integrated peak areas for OPW-Ru treated (red) and untreated (green) reactions obtained after QuSHAPE software processing. (B) Normalized RNA reactivity as a function of the nucleotide position. RNA reactivity is colored according to the scale shown on the right. Values correspond to the mean ± SD of three independent experiments.

This Article

  1. Published in Advance January 12, 2016, doi: 10.1261/rna.054353.115 RNA 22: 330-338

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