Long-range RNA pairings contribute to mutually exclusive splicing

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 4.
FIGURE 4.

Regulation of mutually exclusive splicing in relative pairing strength-dependent mode. (A) The effect on exon 4 inclusion by simultaneously changing the upstream and downstream pairing strength. C1–C6 denotes the combined mutations on dual pairings (Supplemental Fig. S4C). (B) Quantization of the data in A. Data are expressed as percentages of the mean ± SD from three independent experiments.

This Article

  1. Published in Advance November 9, 2015, doi: 10.1261/rna.053314.115 RNA 22: 96-110

Current Issue

  1. July 2026, 32 (7)
  1. Current Issue
  1. Alert me to new issues of RNA