FIGURE 3.
Dual RNA pairing may confer a dynamic range to the regulation of alternative splicing. (A) Comparison of the effect of upstream RNA pairing (stem I) on exon 4.2 inclusion in the presence versus absence of competition from stem II. “D” and “d” denote tunable breadth in the presence versus absence of competition from stem II. (B) Comparison of the effect of downstream RNA pairing (stem II) on exon 4.1 inclusion in the presence versus absence of competition from stem I. Data are expressed as percentages of the mean ± SD from three independent experiments.
