Heatmaps representing miRNA expression. (A) Heatmap of miRNA expression by LNA microarray in human osteoblasts from eight males and 11 females. Out of the 251 expressed miRNAs, a heatmap was generated for the 24 miRNAs differentially expressed by log2 (Hy3/Hy5) ratios with a variation across all samples having SD > 0.50. For comparison, expression levels for hsa-miR-125b are shown below the 24 DE miRNAs. (B) Heatmap depicting variation in miRNA expression between females and males. Out of the expressed miRNA, nine exhibited differential expression levels between males and females based on log2 (Hy3/Hy5) ratios significantly different between males and females using a two-tailed t-test and P-values <0.05. Clustering was made and heatmaps were processed and displayed using MultiExperiment Viewer.
