Profiling ribonucleotide modifications at full-transcriptome level: a step toward MS-based epitranscriptomics

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FIGURE 1.
FIGURE 1.

Representative ESI-MS spectrum of total RNA digest obtained from S. cerevisiae grown in YPD medium. The enlargement shows the region containing the majority of the PTMs. Signals marked with (*) are hits from our custom modifications registry; (Δ), proton-bound dimers of the most abundant species in the spectrum; (‡), METLIN hits; (o), species detected also in the blank.

This Article

  1. Published in Advance May 20, 2015, doi: 10.1261/rna.049429.114 RNA 21: 1361-1374

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