Conserved RNA secondary structures and long-range interactions in hepatitis C viruses

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

FIGURE 4.
FIGURE 4.

Alignment based secondary structures of the X-tail using sequences of 19 isolates. (Top) RNAalifold base-pairing probability matrix of the X-tail region. (A) Consensus secondary structure without applying any constraints. (B) Consensus secondary structure using constraints that force the postulated structure of Blight and Rice (1997). (C,D) Previously unknown secondary structures of the X-tail. All alternative structures contain SLI but show shifted hairpins compared with DLS or SLII.

This Article

  1. RNA 21: 1219-1232