Noncoding RNAs that associate with YB-1 alter proliferation in prostate cancer cells

Characteristics of YB-1–associated short RNAs. (A) Analysis of distinct YB-1–associated short RNAs (shyRNAs) after removal of input RNAs. (B) The RNY3 RNA is matched to YB-1–associated shyRNAs (blue) and low abundance small RNAs (black) that preferentially derive from either the 5′ or 3′ ends of RNY3. The y-axis represents the number of reads while the x-axis shows the genomic location of the reads. The most abundant read is nearly identical to RNY3. (C) Small RNAs preferentially match to the 5′ and 3′ ends of shyRNAs. (D) Correlation between shyRNAs, small RNAs, and mRNAs in PC-3 cells. (E) qPCR validation of different classes of small and shyRNAs.