RNA-seq profiles of crRNAs associated with the Csa, Cst, and Cmr complexes and in total RNA. The number of reads (in thousands) of crRNAs-associated with each complex (extracted from immune pellets of Cas3″, Csa2, Cas5t, Cst2, Cmr2) compared with crRNAs in total RNA (extracted from untreated S100 extract) that map to CRISPR locus 5 are shown. A higher resolution image of three crRNAs is highlighted in the box on the right. Reads mapping to both the sense (red, transcribed from upstream leader) and antisense (blue) strand are indicated. The black boxes at the top correspond to CRISPR repeats interspersed by guide sequences shown as black lines.
