RNAi, the guiding principle and keeping family happy
- Department of Microbiology, Ohio State Biochemistry Program and The Center for RNA Biology, The Ohio State University, Columbus, Ohio 43210, USA
- Corresponding author: alfonzo.1{at}osu.edu
This extract was created in the absence of an abstract.
I am a relative newcomer to the RNA field and have knowingly worked on RNA since 1995. You may say that my interest in RNA literally started with the RNA journal. Having to choose my favorite topic in RNA in the last 20 years is worse than asking a good parent to choose a favorite child. What compounds the problem is that in this particular case the “family” is quite extensive and includes, in the last 20 years alone, 612,536 siblings (entries in PubMed) that harbor the word “RNA.” Nonetheless, at the risk of offending my extensive and extended family, choose I must. For me the single most important discovery has to meet two major, yet simple, criteria: 1) it must impact fields beyond that from which the discovery was made; 2) it must generate a principle or concept that can be applicable to thinking about other unresolved scientific questions. …
