Coffee with Ribohipster
- Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA
- Corresponding author: ares{at}ucsc.edu
This extract was created in the absence of an abstract.
Back in '95, things were different, not like they are now. To help me recall the last two decades, I went out for coffee with a local Santa Cruz eccentric known as Ribohipster. He has a decided preference for artisanal science in an era of corporatized big government projects. Not one to consort with consortia, he resists the idea of trading a solid finding brought forth with one's own hands for a wheelbarrow of government-purchased, industrially manufactured datinos (103 datinos = one piece of data). He is wary of giving up too much of the art. I can see that his nostalgic fondness for vintage RNA research is going to color these reflections.
Back in '95 my lab had several things on its mind. Rhonda Perriman rigged our inside-out group I intron that made RNA circles to make an infinite open reading frame mRNA. Escherichia coli ribosomes circumnavigated this …
