Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs

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FIGURE 4.
FIGURE 4.

Comparison to other KH-QUA2 proteins. The tertiary structures of the KH-QUA2 domains of Msl5, QKI (pdb JVH), GLD-1 (pdb 4JVY), and SF1 (pdb 1K1G) were aligned and then offset horizontally. The RNA ligands are depicted as stick models. The nucleobase sequences of the RNAs are shown below the structures; positions of identity with respect to the yeast consensus branchpoint are shaded in gold.

This Article

  1. Published in Advance January 13, 2015, doi: 10.1261/rna.048942.114 RNA 21: 401-414

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