FIGURE 9.
Metabolic profiles and miR-130a expression in HBV transgenic mice. (A) HBV DNA replication was detected in the liver of HBV transgenic mice by Southern. Samples in each lane are from each individual mouse. The result here is representative of at least three independent experiments. (B) Reduced expression of miR-130a in HBV transgenic mice was compared with that of the parental control mice by stem–loop qPCR analysis. (C) Relative to the wild-type control mice (naive), HBV transgenic mice exhibited decreased expression of NF-κB/p65 and increased expression of HBV core protein, PGC1α, PEPCK, G6Pase, PPARγ.
