Expedited quantification of mutant ribosomal RNA by binary deoxyribozyme (BiDz) sensors

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FIGURE 3.
FIGURE 3.

Fluorescent response of the sensors BiDz0, BiDz-wt, or BiDz-m04 in the presence of different concentrations (0–800 pM) of in vitro 23S rRNA transcripts. (A) Wild-type RNA transcript (23S rRNA-wt) and (B) mutant m04 RNA transcript (23S rRNA-04). (Inset) Enlarged linear fragments of the curves in B. BiDz sensors were incubated with the transcripts for 1 h at 54°C.

This Article

  1. Published in Advance August 19, 2015, doi: 10.1261/rna.052613.115 RNA 21: 1834-1843

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