eIF4AII is dispensable for miRNA-mediated gene silencing

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FIGURE 2.
FIGURE 2.

(A) Loss of eIF4AII does not affect global translation or cellular viability. Quantitation of protein synthesis in NIH/3T3 and eIF4AIIem1JP cells. Protein synthesis was determined as described in Materials and Methods. N = 3 biological replicates (performed in technical duplicates) ± SEM. (B) Population doubling level (PDL) of NIH/3T3 and eIF4AIIem1JP cells. N = 3 biological replicates (performed in technical duplicates) ± SEM.

This Article

  1. Published in Advance August 18, 2015, doi: 10.1261/rna.052225.115 RNA 21: 1826-1833

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