Prevalent RNA recognition motif duplication in the human genome

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FIGURE 4.
FIGURE 4.

An RBP family with ancient RRM duplications. (A) The diagram of PABP proteins from five species (H. sapiens, M. musculus, D. melanogaster, C. elegans, and S. pombe). The members in this protein family contain one to four RRMs, and some also contain a C-terminal PABC domain. Each RRM is colored according to their relative positions within the protein. (B) The phylogenetic tree of RRMs in the PABP family was visualized via TreeView. The RRMs are colored in the same scheme as in panel A, and the RRMs in the same position are more similar to each other across all species.

This Article

  1. RNA 20: 702-712