A tRNA body with high affinity for EF-Tu hastens ribosomal incorporation of unnatural amino acids

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FIGURE 1.
FIGURE 1.

A tRNA based on tRNAAla (tRNAAlaB) charged with natural and unnatural AAs. (A) Natural and unnatural L-AAs used in our kinetics studies. (B) Synthetic tRNAAlaB (Zhang et al. 2007), which is an unmodified tRNA based on natural E. coli tRNAAla (black with purple anticodon; tRNA modifications are in green) with changes in blue.

This Article

  1. Published in Advance March 26, 2014, doi: 10.1261/rna.042234.113 RNA 20: 632-643

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