RF3:GTP promotes rapid dissociation of the class 1 termination factor

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FIGURE 6.
FIGURE 6.

Model for RF3 mechanism of action in translation termination. In this model, following peptide release, with the ribosome in a nonrotated state, RF3:GTP binds the termination complex. The ribosome then undergoes a conformational change to the rotated state, thereby promoting RF1 dissociation.

This Article

  1. Published in Advance March 25, 2014, doi: 10.1261/rna.042523.113 RNA 20: 609-620

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