Association of a peptoid ligand with the apical loop of pri-miR-21 inhibits cleavage by Drosha

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FIGURE 4.
FIGURE 4.

Compounds identified in the microarray screens. Compounds 2–9 were obtained from Sublibrary A and compounds 10–12 were obtained from Sublibrary B. Solution-phase dissociation constants (µM) measured by monitoring 2-ap fluorescence for RNAs I and II are shown. Reported dissociation constants are the mean ± SD for three independent determinations.

This Article

  1. Published in Advance February 4, 2014, doi: 10.1261/rna.042911.113 RNA 20: 528-539

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