Direct evidence for RNA–RNA interactions at the 3′ end of the Hepatitis C virus genome using surface plasmon resonance

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FIGURE 6.
FIGURE 6.

Kinetic analysis of SL2 binding to itself. SL2WT was biotinylated at its 5′ end and immobilized on a streptavidin-coated CM5 sensor chip. SL2 hairpins were injected in duplicate at 500 nM as indicated by the arrows. The experiments were performed at 10°C and at a flow rate of 50 µL/min. The truncated version of 5BSL3.2, mini5BSL3.2, was also injected over the SL2 functionalized surface.

This Article

  1. Published in Advance May 7, 2013, doi: 10.1261/rna.037606.112 RNA 19: 982-991

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